#shoutcureaids

BECAUSE WE HAVE THE SCIENCE TO CREATE A CURE
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THE "BERLIN PATIENT"—
FIRST AND ONLY MAN
CURED OF AIDS
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Timothy Ray Brown, known widely as the “Berlin Patient,” was hiv+ when he received a stem cell transplant from an hiv-resistant donor and was cured of aids
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IN 2019, THE “LONDON PATIENT” BECAME THE SECOND MAN CURED OF AIDS, BY THE SAME EXACT METHOD AS THE BERLIN PATIENT. HE RECEIVED A STEM CELL TRANSPLANT CONTAINING THE DELTA 32 MUTATION, AND BECAME THE SECOND MAN CURED.3

THE SCIENCE BEHIND THE CURE
In most people, HIV can attach to a protein on the cell called CCR52
People who are HIV-Resistant have a shortened form of the protein known as the DELTA 32 MUTATION2
When transplanted with the delta 32 mutation,
People who are hiv+ can be cured
Chromovert® technology—accomplishing the unthinkable
RFTCA PRESIDENT KAMBIZ SHEKDAR INVENTED CHROMOVERT® TECHNOLOGY, WHICH HAS BEEN USED TO MANIPULATE CELLS WITH ASTONISHING RESULTS
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created cells that mimic human taste
for leading food companies
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created potent pain blockers to
prevent pain, surpassing the
effects of morphine
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Mission: create the delta 32 mutation, which
will give rise to an hiv-resistant immune
system, ultimately in the same way as
the berlin patient.
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the rftca is using a biotechnology
that can accomplish another unthinkable:
creating curative stem cells that can cure aids.

References: 1. Osborne H. Timothy Ray Brown: World's only person cured of HIV speaks about stem cell transplant experience. International Business Times UK. January 6, 2015. www.ibtimes.co.uk/timothyraybrownworldsonlypersoncuredhivspeaksaboutstemcelltransplantexperience1482179. Accessed February 24, 2016.
2. Alkhatib G. The biology of CCR5 and CXCR4. Curr Opin HIV AIDS. 2009;4(2):96-103.
3. Mandavilli A. H.I.V. Is Reported Cured in a Second Patient, a Milestone in the Global AIDS Epidemic. The New York Times. www.nytimes.com/2019/03/04/health/aids-cure-london-patient.html. Published March 4, 2019. Accessed March 8, 2019.

FAQs

HIV stands for human immuno-deficiency virus. AIDS stands for acquired immune deficiency syndrome.

HIV is transmitted through blood, semen, vaginal secretion, and breast milk. You can become infected with HIV in the following ways:

  • Having unprotected sex with an infected person
  • Sharing sharp objects, such as needles, with an infected person
  • Receiving a blood transfusion
  • Being born to or breastfeeding from a mother who is HIV+

Stigma and discrimination are the main reasons people resist getting tested, which leads to late diagnoses and a greater chance for HIV to progress to AIDS, making treatment less effective and increasing the likelihood of transmission to others. People who have experienced stigma are four times more likely to report poor access to care. Stigma also affects the emotional well-being of those with HIV, as it leads to loss of hope and feelings of worthlessness.

Standard AR therapy consists of a combination of at least three AR drugs that work to suppress the virus and stop the progression of the disease.

Side effects can include nausea, vomiting, bleeding events, diabetes, cardiovascular disease, and toxic epidermal necrosis. If you or someone you know is taking ARs and experiencing side effects, talk to your doctor to figure out the best treatment plan.

People are resistant to HIV if they have a natural genetic mutation on their cells that doesn't allow HIV to latch on.

The cure method used for the Berlin Patient would involve a stem cell transplant. Since stem-cell transplants can cost up to $250,000 and is not viable for many people, the Delta 32 mutation would have to be given without a transplant. This means the Delta 32 mutation would have to be created, instead of donated.

It is extremely rare to find someone who is a bone marrow match and rarer still to find someone who is also HIV-resistant. Therefore, the Berlin Patient’s procedure method is not broadly applicable. This is why our Chromovert® technology is so important in creating curative stem cells, alleviating the need to find rare matches.

Chromovert® is a proprietary cellular technology that can isolate and enrich rare cells with optimal, desired genetics. It has successfully isolated cells that mimic human taste buds for leading food companies like Coca-Cola®, Nestle®, and Kraft®, as well as pain-blocker cells that allowed the discovery of new drugs that surpass the effects of morphine. It is now being used to create the Delta 32 mutation, which would give rise to an HIV-resistant immune system, ultimately curing the person of AIDS.

RFTCA President Kambiz Shekdar realized that the biotechnology he invented called Chromovert® Technology can create curative stem cells and replicate the cure used on the Berlin and London Patients. Once Kambiz realized his technology may hold the keys to a cure, he sought out organizations and experts that could help him achieve it.

We welcome people from all walks of life to help us in our cause for a cure. Go to the Get Involved page to donate, volunteer, and share your story.

An alliance such as ours reflects diverse thinking and experiences. We believe we need experts from scientific, clinical, manufacturing, medical, legal, financial, philanthropic, creative, artistic, and other areas in order to succeed. We welcome those living with AIDS, taking care of someone with AIDS, or affected by AIDS in some other way to take a seat at the table and join us. We need to hear stories from different people from all walks of life to make the most meaningful impact.

They don’t teach you the truth about HIV

CONTACT US

If you have a question or comment, please write to us using the contact information below. We'd love to hear from you.

Email
cure@RFTCA.org

Address Research Foundation to Cure AIDS
c/o Kambiz Shekdar
40 Remsen Street
Brooklyn, NY 11201